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Proceedings Paper

Optical multi-frequency swept sensing for wide-field vibration measurement of interior surfaces in biological tissue
Author(s): S. Choi; F. Nin; H. Hibino; T. Suzuki
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Paper Abstract

Multifrequency sensing technique adopting the wide field heterodyne detection technique is demonstrated for interior surface vibration measurements in thick biological tissue. These arrangements allow obtaining not only 3D tomographic images but also various vibration parameters such as spatial amplitude, phase, and frequency, with high temporal and transverse resolutions over a wide field. The axial resolution and the accuracy of vibration amplitude measurement were estimated to be 2.5 μm and 3 nm, respectively. This wide-field tomographic sensing method can be applied for measuring microdynamics of a variety of biological samples, thus contributing to the progress in life sciences research.

Paper Details

Date Published: 9 December 2015
PDF: 7 pages
Proc. SPIE 9792, Biophotonics Japan 2015, 97920Q (9 December 2015); doi: 10.1117/12.2204984
Show Author Affiliations
S. Choi, Niigata Univ (Japan)
F. Nin, Niigata Univ. School of Medicine (Japan)
H. Hibino, Niigata Univ. School of Medicine (Japan)
T. Suzuki, Niigata Univ. (Japan)

Published in SPIE Proceedings Vol. 9792:
Biophotonics Japan 2015
Takashige Omatsu; Yoshio Hayasaki; Yusuke Ogura; Yasuyuki Ozeki; Seigo Ohno, Editor(s)

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