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Proceedings Paper

Examining pharmaceuticals using terahertz spectroscopy
Author(s): Kateřina Sulovská; Vojtěch Křesálek
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Paper Abstract

Pharmaceutical trafficking is common issue in countries where they are under stricter dispensing regime with monitoring of users. Most commonly smuggled pharmaceuticals include trade names Paralen Plus, Modafen, Clarinase repetabs, Aspirin complex, etc. These are transported mainly from Eastern Europe (e.g. Poland, Ukraine, Russia) to countries like Czech Republic, which is said to have one of the highest number of methamphetamine producers in Europe. The aim of this paper is to describe the possibility of terahertz spectroscopy utilization as an examining tool to distinguish between pharmaceuticals containing pseudoephedrine compounds and those without it. Selected medicaments for experimental part contain as an active ingredient pseudoephedrine hydrochloride or pseudoephedrine sulphate. Results show a possibility to find a pseudoephedrine compound spectra in samples according to previously computed and experimentally found ones, and point out that spectra of same brand names pills may vary according to their expiration date, batch, and amount of absorbed water vapours from ambience. Mislead spectrum also occurs during experimental work in a sample without chosen active ingredient, which shows persistent minor inconveniences of terahertz spectroscopy. All measurement were done on the TPS Spectra 3000 instrument.

Paper Details

Date Published: 21 October 2015
PDF: 6 pages
Proc. SPIE 9651, Millimetre Wave and Terahertz Sensors and Technology VIII, 965103 (21 October 2015); doi: 10.1117/12.2194585
Show Author Affiliations
Kateřina Sulovská, Tomas Bata Univ. of Zlin (Czech Republic)
Vojtěch Křesálek, Tomas Bata Univ. of Zlin (Czech Republic)

Published in SPIE Proceedings Vol. 9651:
Millimetre Wave and Terahertz Sensors and Technology VIII
Neil A. Salmon; Eddie L. Jacobs, Editor(s)

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