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Proceedings Paper • Open Access

Nano-bio-optomechanics: nanoaperture tweezers probe single nanoparticles, proteins, and their interactions
Author(s): Reuven Gordon

Paper Abstract

Nanoparticles in the single digit nanometer range can be easily isolated and studied with low optical powers using nanoaperture tweezers. We have studied individual proteins and their interactions with small molecules, DNA and antibodies. Recently, using the fluctuations of the trapped object, we have pioneered a new way to "listen" to the vibrations of nanoparticles in the 100 GHz - 1 THz range; the approach is called extraordinary acoustic Raman (EAR). EAR gives unprecedented low frequency spectra of individual proteins in solution, allowing for identification and analysis, as well as probing their role in biological functions. We have also used EAR to study the elastic properties, shape and size of various individual nanoparticles.

Paper Details

Date Published: 1 September 2015
PDF: 6 pages
Proc. SPIE 9544, Metamaterials, Metadevices, and Metasystems 2015, 954403 (1 September 2015); doi: 10.1117/12.2193785
Show Author Affiliations
Reuven Gordon, Univ. of Victoria (Canada)

Published in SPIE Proceedings Vol. 9544:
Metamaterials, Metadevices, and Metasystems 2015
Nader Engheta; Mikhail A. Noginov; Nikolay I. Zheludev, Editor(s)

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