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Proceedings Paper

Boundary element method for optical force calibration in microfluidic dual-beam optical trap
Author(s): Mehmet E. Solmaz; Barbaros Ҫetin; Besim Baranoğlu; Murat Serhathoğlu; Necmi Biyikli
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Paper Abstract

The potential use of optical forces in microfluidic environment enables highly selective bio-particle manipulation. Manipulation could be accomplished via trapping or pushing a particle due to optical field. Empirical determination of optical force is often needed to ensure efficient operation of manipulation. The external force applied to a trapped particle in a microfluidic channel is a combination of optical and drag forces. The optical force can be found by measuring the particle velocity for a certain laser power level and a multiplicative correction factor is applied for the proximity of the particle to the channel surface. This method is not accurate especially for small microfluidic geometries where the particle size is in Mie regime and is comparable to channel cross section. In this work, we propose to use Boundary Element Method (BEM) to simulate fluid flow within the micro-channel with the presence of the particle to predict drag force. Pushing experiments were performed in a dual-beam optical trap and particle’s position information was extracted. The drag force acting on the particle was then obtained using BEM and other analytical expressions, and was compared to the calculated optical force. BEM was able to predict the behavior of the optical force due to the inclusion of all the channel walls.

Paper Details

Date Published: 25 August 2015
PDF: 8 pages
Proc. SPIE 9548, Optical Trapping and Optical Micromanipulation XII, 95481D (25 August 2015); doi: 10.1117/12.2190319
Show Author Affiliations
Mehmet E. Solmaz, Izmir Katip Ҫelebi Univ. (Turkey)
Bilkent Univ. (Turkey)
Barbaros Ҫetin, Bilkent Univ. (Turkey)
Besim Baranoğlu, Atilim Üniv. (Turkey)
Murat Serhathoğlu, Bilkent Univ. (Turkey)
Necmi Biyikli, Bilkent Univ. (Turkey)

Published in SPIE Proceedings Vol. 9548:
Optical Trapping and Optical Micromanipulation XII
Kishan Dholakia; Gabriel C. Spalding, Editor(s)

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