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Proceedings Paper

Switchable bioelectronics on graphene interface (Presentation Recording)
Author(s): Onur Parlak; Ashutosh Tiwari; Anthony P. F. Turner
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Paper Abstract

Smart and flexible bioelectronics on graphene have emerged as a new frontier in the field of biosensors and bioelectronics. Graphene has begun to be seen as an ideal signal transducer and a promising alternative for the production of low-cost bioelectronic devices.1-2 However, biological systems used in these devices suffer from a lack of control and regulation. There is an obvious need to develop “switchable” and “smart” interfaces for both fundamental and applied studies. Here, we report the fabrication of a stimuli-responsive graphene interface, which is used to regulate biomolecular reactions. The present study aims to address the design and development of a novel auto-switchable graphene bio-interface that is capable of positively responding, by creating smart nanoarchitectures. By changing the external conditions such as temperature, light and pH of the medium, we acheived control of the biochemical interactions. In the negative mode, access of an associated enzyme to its substrate is largely restricted, resulting in a decrease in the diffusion of reactants and the consequent activity of the system. In contrast, the biosubstrate could freely access the enzyme facilitating bioelectrocatalysis in a positive response. Using electrochemical techniques, we demonstrated that interfacial bio-electrochemical properties can be tuned by modest changes in conditions. Such an ability to independently regulate the behaviour of the interface has important implications for the design of novel bioreactors, biofuel cells and biosensors with inbuilt self-control features.

Paper Details

Date Published: 5 October 2015
PDF: 1 pages
Proc. SPIE 9550, Biosensing and Nanomedicine VIII, 95500H (5 October 2015); doi: 10.1117/12.2190231
Show Author Affiliations
Onur Parlak, Linköping Univ. (Sweden)
Ashutosh Tiwari, Linköping Univ (Sweden)
Anthony P. F. Turner, Linköping Univ. (Sweden)

Published in SPIE Proceedings Vol. 9550:
Biosensing and Nanomedicine VIII
Hooman Mohseni; Massoud H. Agahi; Manijeh Razeghi, Editor(s)

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