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Proceedings Paper

Gallium arsenide based surface plasmon resonance for glucose monitoring
Author(s): Harshada Patil; Vani Sane; Sriram G.; Indumathi T.S.; Preeta Sharan
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Paper Abstract

The recent trends in the semiconductor and microwave industries has enabled the development of scalable microfabrication technology which produces a superior set of performance as against its counterparts. Surface Plasmon Resonance (SPR) based biosensors are a special class of optical sensors that become affected by electromagnetic waves. It is found that bio-molecular recognition element immobilized on the SPR sensor surface layer reveals a characteristic interaction with various sample solutions during the passage of light. The present work revolves around developing painless glucose monitoring systems using fluids containing glucose like saliva, urine, sweat or tears instead of blood samples. Non–invasive glucose monitoring has long been simulated using label free detection mechanisms and the same concept is adapted. In label-free detection, target molecules are not labeled or altered, and are detected in their natural forms. Label-free detection mechanisms involves the measurement of refractive index (RI) change induced by molecular interactions. These interactions relates the sample concentration or surface density, instead of total sample mass. After simulation it has been observed that the result obtained is highly accurate and sensitive. The structure used here is SPR sensor based on channel waveguide. The tools used for simulation are RSOFT FULLWAVE, MEEP and MATLAB etc.

Paper Details

Date Published: 17 July 2015
PDF: 8 pages
Proc. SPIE 9524, International Conference on Optical and Photonic Engineering (icOPEN 2015), 95242E (17 July 2015); doi: 10.1117/12.2189668
Show Author Affiliations
Harshada Patil, Vemana Institute of Technology (India)
Vani Sane, The Oxford College of Engineering (India)
Sriram G., The Oxford College of Engineering (India)
Indumathi T.S., VTU Ctr. for Advanced Technology (India)
Preeta Sharan, The Oxford College of Engineering (India)


Published in SPIE Proceedings Vol. 9524:
International Conference on Optical and Photonic Engineering (icOPEN 2015)
Anand K. Asundi; Yu Fu, Editor(s)

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