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Proceedings Paper

Liquid sensor based bio-chip for DNA analysis of cancer using photonic crystal
Author(s): Harshada Patil; Nischitha R.; Indumathi T. S.; Preeta Sharan
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Paper Abstract

Silicon photonics is poised to revolutionize bio-sensing applications, specifically in medical diagnostics. The need for cost effective and reliable bio-sensors in medical applications is an ever growing and everlasting one. In this synopsis we have designed a 2-D hexagonal photonic crystal ring resonator based bio-sensor that is able to detect lung cancer from blood. Simulation and analysis has been done for normal DNA and the cancer affected DNA in blood. The intensity level of transmission spectrum has been observed. Finite Difference Time Domain (FDTD) method is used for analysis. MEEP (MIT Electromagnetic Equation Propagation) tool and RSOFT Photonic Suite CAD tool are used designing the photonic crystal sensor. The results show that for small changes in the refractive index of the input samples there is a significant shift in wavelength and amplitude. Thus the sensor is highly sensitive for change in refractive index and hence differentiating normal and cancer affected DNA.

Paper Details

Date Published: 17 July 2015
PDF: 6 pages
Proc. SPIE 9524, International Conference on Optical and Photonic Engineering (icOPEN 2015), 95241Y (17 July 2015); doi: 10.1117/12.2189606
Show Author Affiliations
Harshada Patil, Vemana Institute of Technology (India)
Nischitha R., The Oxford College of Engineering (India)
Indumathi T. S., VTU Ctr. for Advanced Technology (India)
Preeta Sharan, The Oxford College of Engineering (India)

Published in SPIE Proceedings Vol. 9524:
International Conference on Optical and Photonic Engineering (icOPEN 2015)
Anand K. Asundi; Yu Fu, Editor(s)

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