Share Email Print
cover

Proceedings Paper

Probabilistic approach for sensing performances of localized surface plasmon resonance biosensors
Author(s): Heejin Yang; Wonju Lee; Taewon Hwang; Donghyun Kim
Format Member Price Non-Member Price
PDF $14.40 $18.00
cover GOOD NEWS! Your organization subscribes to the SPIE Digital Library. You may be able to download this paper for free. Check Access

Paper Abstract

We analyze sensing performances of localized surface plasmon resonance biosensors based on the overlap between target distribution and local field intensity produced by silver nanoislands in three detection models of non-specific, non-colocalized, and colocalized detection. The behavior of biomolecules was modeled to follow a probabilistic model using Poisson distribution. The results have found that the colocalized detection achieves the highest overlap signature with the smallest uncertainty and can enhance the limit of detection by more than 10000 times compared to conventional non-specific detection.

Paper Details

Date Published: 8 July 2015
PDF: 7 pages
Proc. SPIE 9523, International Conference on Nano-Bio Sensing, Imaging, and Spectroscopy 2015, 95230L (8 July 2015); doi: 10.1117/12.2189429
Show Author Affiliations
Heejin Yang, Yonsei Univ. (Korea, Republic of)
Wonju Lee, Yonsei Univ. (Korea, Republic of)
Taewon Hwang, Yonsei Univ. (Korea, Republic of)
Donghyun Kim, Yonsei Univ. (Korea, Republic of)


Published in SPIE Proceedings Vol. 9523:
International Conference on Nano-Bio Sensing, Imaging, and Spectroscopy 2015
Donghyun Kim; Min-Gon Kim; Seung-Han Park, Editor(s)

© SPIE. Terms of Use
Back to Top