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Proceedings Paper

Treatments of the oral leukoplakia by laser
Author(s): M. Capocci; M. Mohsen; R. Lo Giudice; A. Del Vecchio; G. Gaimari; L. Tribolati; G. Palaia; U. Romeo
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Paper Abstract

Oral leukoplakia is catalogued under the group of “potentially malignant disorders”. In daily practice, the World Health Organization definition “white patch or plaque that cannot be characterized clinically or histologically as any other disease” is completed by including the observation that it cannot be removed by simple scraping, thereby distinguishing it from pseudo-membranous candidiasis. The aim of this study is to find a definitive treatment of oral leukoplakia, because of its recurrence and its potentiality to the malignant transformation. There are currently different approaches to oral leukoplakia: scalpel surgery, systemic therapy (carotenoids, vitamins, etc.), electro-cauterization, cryotherapy and the use of the laser. In every lesion, biopsy and histological analysis has been performed to identify the stage and classification of the oral leukoplakia.

Laser can be used for the complete excision of the lesion (which is more effective, but also more invasive), for the photodynamic therapy (non-invasive procedure, which requires several applications) or for the vaporization of the lesion (very precise treatment and relatively easy to perform). Laser treatments have shown better healing, less soft tissues retraction and less post-operative pain, comparing with traditional surgery. The use of systemic therapies and smoking habit interruption (where present) has been also useful to reduce the lesions before the clinical treatments. The treatment has always to be supported by histological analysis to identify the risk and consequently planning the clinical approach.

Paper Details

Date Published: 22 March 2016
PDF: 8 pages
Proc. SPIE 9670, Sixth International Conference on Lasers in Medicine, 967009 (22 March 2016); doi: 10.1117/12.2189243
Show Author Affiliations
M. Capocci, Sapienza Univ. of Rome (Italy)
M. Mohsen, Sapienza Univ. of Rome (Italy)
R. Lo Giudice, Sapienza Univ. of Rome (Italy)
A. Del Vecchio, Sapienza Univ. of Rome (Italy)
G. Gaimari, Sapienza Univ. of Rome (Italy)
L. Tribolati, Sapienza Univ. of Rome (Italy)
G. Palaia, Sapienza Univ. of Rome (Italy)
U. Romeo, Sapienza Univ. of Rome (Italy)

Published in SPIE Proceedings Vol. 9670:
Sixth International Conference on Lasers in Medicine
Darinca Carmen Todea; Adrian Gh. Podoleanu; Virgil-Florin Duma, Editor(s)

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