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Proceedings Paper

High-contrast imaging of mycobacterium tuberculosis using third-harmonic generation microscopy
Author(s): Bo Ram Kim; Eungjang Lee; Seung-Han Park
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Paper Abstract

Nonlinear optical microcopy has become an important tool in investigating biomaterials due to its various advantages such as label-free imaging capabilities. In particular, it has been shown that third-harmonic generation (THG) signals can be produced at interfaces between an aqueous medium (e.g. cytoplasm, interstitial fluid) and a mineralized lipidic surface. In this work, we have demonstrated that label-free high-contrast THG images of the mycobacterium tuberculosis can be obtained using THG microscopy.

Paper Details

Date Published: 8 July 2015
PDF: 4 pages
Proc. SPIE 9523, International Conference on Nano-Bio Sensing, Imaging, and Spectroscopy 2015, 95230G (8 July 2015); doi: 10.1117/12.2187632
Show Author Affiliations
Bo Ram Kim, Yonsei Univ. (Korea, Republic of)
Eungjang Lee, CELIA, Univ. de Bordeaux, CNRS (France)
Seung-Han Park, Yonsei Univ. (Korea, Republic of)


Published in SPIE Proceedings Vol. 9523:
International Conference on Nano-Bio Sensing, Imaging, and Spectroscopy 2015
Donghyun Kim; Min-Gon Kim; Seung-Han Park, Editor(s)

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