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Proceedings Paper

Portable LED-induced autofluorescence imager with a probe of L shape for oral cancer diagnosis
Author(s): Ting-Wei Huang; Yu-Cheng Lee; Nai-Lun Cheng; Yung-Jhe Yan; Hou-Chi Chiang; Jin-Chern Chiou; Ou-Yang Mang
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Paper Abstract

The difference of spectral distribution between lesions of epithelial cells and normal cells after excited fluorescence is one of methods for the cancer diagnosis. In our previous work, we developed a portable LED Induced autofluorescence (LIAF) imager contained the multiple wavelength of LED excitation light and multiple filters to capture ex-vivo oral tissue autofluorescence images. Our portable system for detection of oral cancer has a probe in front of the lens for fixing the object distance. The shape of the probe is cone, and it is not convenient for doctor to capture the oral image under an appropriate view angle in front of the probe. Therefore, a probe of L shape containing a mirror is proposed for doctors to capture the images with the right angles, and the subjects do not need to open their mouse constrainedly. Besides, a glass plate is placed in probe to prevent the liquid entering in the body, but the light reflected from the glass plate directly causes the light spots inside the images. We set the glass plate in front of LED to avoiding the light spots. When the distance between the glasses plate and the LED model plane is less than the critical value, then we can prevent the light spots caused from the glasses plate. The experiments show that the image captured with the new probe that the glasses plate placed in the back-end of the probe has no light spots inside the image.

Paper Details

Date Published: 27 August 2015
PDF: 6 pages
Proc. SPIE 9594, Medical Applications of Radiation Detectors V, 95940J (27 August 2015); doi: 10.1117/12.2187176
Show Author Affiliations
Ting-Wei Huang, National Chiao Tung Univ. (Taiwan)
Yu-Cheng Lee, National Chiao-Tung Univ. (Taiwan)
Nai-Lun Cheng, National Chiao Tung Univ. (Taiwan)
Yung-Jhe Yan, National Chiao Tung Univ. (Taiwan)
Hou-Chi Chiang, National Chiao Tung Univ. (Taiwan)
Jin-Chern Chiou, National Chiao Tung Univ. (Taiwan)
China Medical Univ. (Taiwan)
Ou-Yang Mang, National Chiao Tung Univ. (Taiwan)


Published in SPIE Proceedings Vol. 9594:
Medical Applications of Radiation Detectors V
H. Bradford Barber; Lars R. Furenlid; Hans N. Roehrig, Editor(s)

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