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Proceedings Paper

In situ and ultrasensitive DNA detection based on a graphene-coated silica fiber taper interferometer
Author(s): Bo Yu; Yunyun Huang; Mingfei Ding; Yang Ran; Bai-Ou Guan
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Paper Abstract

A high sensitivity biosensor based on graphene coated silica fiber taper interferometer is presented. Thank to the combination of graphene coating and the optical fiber taper interferometer structure, the biosensor demonstrates improved DNA concentration sensitivity of 0.4 nm/log M and good linearity, yielding the lower detection limit of 10 pM. This high sensitivity and biocompatibility enable the biosensor in precision in-situ DNA detection, even in ultra-diluted DNA solution. Based on our work, the graphene coating could convert the concentration information of target molecular to the RI variation, and further to light signals by the taper.

Paper Details

Date Published: 1 July 2015
PDF: 4 pages
Proc. SPIE 9655, Fifth Asia-Pacific Optical Sensors Conference, 96551F (1 July 2015); doi: 10.1117/12.2184221
Show Author Affiliations
Bo Yu, Jinan Univ. (China)
Yunyun Huang, Jinan Univ. (China)
Mingfei Ding, Jinan Univ. (China)
Yang Ran, Jinan Univ. (China)
Bai-Ou Guan, Jinan Univ. (China)

Published in SPIE Proceedings Vol. 9655:
Fifth Asia-Pacific Optical Sensors Conference
Byoungho Lee; Sang-Bae Lee; Yunjiang Rao, Editor(s)

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