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Proceedings Paper

Comparison of the simplified laterally uniform and geometrically realistic optical fiber probe-tissue interface in terms of Monte Carlo simulated diffuse reflectance
Author(s): Peter Naglič; Franjo Pernuš; Boštjan Likar; Miran Bürmen
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Paper Abstract

Diffuse reflectance spectroscopy utilizing optical fiber probes is a useful and simple method for non-invasive determination of biological tissue optical properties. In order to extract the optical properties from the acquired diffuse reflectance spectra, an accurate light propagation model, such as Monte Carlo, is required. The results obtained by the model can significantly depend on the description of the tissue and optical fiber probe geometry. Optical fiber probes commonly comprise fibers arranged into a desired source-detector layout enclosed in a stainless steel ferrule. By using Monte Carlo simulations, we investigate the impact of the stainless steel optical fiber probe-tissue interface on the diffuse reflectance spectra. For this purpose, a commonly used simple laterally uniform optical probe-tissue interface with mismatched refractive indices was compared to the improved optical probe-tissue interface taking into account the fiber layout and the specular reflections from the stainless steel probe tip. The results show that the error introduced into the simulated diffuse reflectance by the simplified probe-tissue interface can easily exceed 5%.

Paper Details

Date Published: 15 July 2015
PDF: 8 pages
Proc. SPIE 9537, Clinical and Biomedical Spectroscopy and Imaging IV, 95370R (15 July 2015); doi: 10.1117/12.2183867
Show Author Affiliations
Peter Naglič, Univ. of Ljubljana (Slovenia)
Franjo Pernuš, Univ. of Ljubljana (Slovenia)
Boštjan Likar, Univ. of Ljubljana (Slovenia)
Miran Bürmen, Univ. of Ljubljana (Slovenia)

Published in SPIE Proceedings Vol. 9537:
Clinical and Biomedical Spectroscopy and Imaging IV
J. Quincy Brown; Volker Deckert, Editor(s)

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