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Proceedings Paper

Spectroscopic imaging of blood vessels only near the skin surface for non-invasive blood glucose measurement
Author(s): Masaru Fujiwara; Shun Sato; Pradeep K. W. Abeygunawardhana; Satoru Suzuki; Akira Nishiyama; Kenji Wada; Ichiro Ishimaru
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Paper Abstract

To realize the non-invasive blood glucose measurement, it will be effective to acquire the spectroscopic imaging of blood vessels only near the skin surface for eliminating other biological-component’s disturbances. Our proposed imaging-type 2-dimensional Fourier spectroscopic imaging can limit the measuring depth into focal plane with high light detection sensitivity. Thus, the proposed method will be suitable for measuring only near the skin surface with detecting weak reflected light from inner biomembrane. But reflectance of skin surface is more than 1000 times larger than inner skin’s reflectance. Paying attention on Fresnel reflection, fingers what were illuminated by p-polarized beam from Brewster's angle were observed with crossed-Nicol dark field optics. We successfully acquired spectroscopic characteristics of hemoglobin at vein area near the skin surface.

Paper Details

Date Published: 15 July 2015
PDF: 5 pages
Proc. SPIE 9537, Clinical and Biomedical Spectroscopy and Imaging IV, 953714 (15 July 2015); doi: 10.1117/12.2183671
Show Author Affiliations
Masaru Fujiwara, Kagawa Univ. (Japan)
Shun Sato, Kagawa Univ. (Japan)
Pradeep K. W. Abeygunawardhana, Kagawa Univ. (Japan)
Satoru Suzuki, Kagawa Univ. (Japan)
Akira Nishiyama, Kagawa Univ. (Japan)
Kenji Wada, Kagawa Univ. (Japan)
Ichiro Ishimaru, Kagawa Univ. (Japan)

Published in SPIE Proceedings Vol. 9537:
Clinical and Biomedical Spectroscopy and Imaging IV
J. Quincy Brown; Volker Deckert, Editor(s)

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