Share Email Print
cover

Proceedings Paper

Mathematical model of depolarization mechanism of conducted vasoreactivity
Format Member Price Non-Member Price
PDF $14.40 $18.00

Paper Abstract

We address the problem of conducted vasodilation, the phenomenon which is also known as functional hyperemia. Specifically, we test the mechanism of nondecremental propagation of electric signals along endothelial cell layer recently hypothesized by Figueroa et al. By means of functional modeling we focus on possible nonlinear mechanisms that can underlie such regenerative pulse transmission (RPT). Since endothelial cells (EC) are generally known as electrically inexcitable, the possible role of ECs in RPT mechanisms is not evident. By means of mathematical modeling we check the dynamical self-consistency of Figueroa's hypothesis, as well as estimate the possible contribution of specific ionic currents to the suggested RPT mechanism.

Paper Details

Date Published: 19 March 2015
PDF: 10 pages
Proc. SPIE 9448, Saratov Fall Meeting 2014: Optical Technologies in Biophysics and Medicine XVI; Laser Physics and Photonics XVI; and Computational Biophysics, 94481J (19 March 2015); doi: 10.1117/12.2179584
Show Author Affiliations
Anastasiia Y. Neganova, Saratov State Univ. (Russian Federation)
Copenhagen Univ. (Denmark)
Elena S. Stiukhina, Saratov State Univ. (Russian Federation)
Dmitry E. Postnov, Saratov State Univ. (Russian Federation)


Published in SPIE Proceedings Vol. 9448:
Saratov Fall Meeting 2014: Optical Technologies in Biophysics and Medicine XVI; Laser Physics and Photonics XVI; and Computational Biophysics
Elina A. Genina; Vladimir L. Derbov; Kirill V. Larin; Dmitry E. Postnov; Valery V. Tuchin, Editor(s)

© SPIE. Terms of Use
Back to Top