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Proceedings Paper

Hybrid microneedles devices for diagnostic and therapeutic applications: fabrication and preliminary results
Author(s): P. Dardano; A. Caliò; J. Politi; V. Di Palma; M. F. Bevilacqua; I. Rea; M. Casalino; A. Di Matteo; I. Rendina; L. De Stefano
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Paper Abstract

Microneedles are newly developed biomedical devices, whose advantages are mainly in the non-invasiveness, discretion and versatility of use both as diagnostics and as therapeutics tool. In fact, they can be used both for drugs delivery in the interstitial fluids and for the analysis of the interstitial fluid. In this work we present the preliminary results for two devices based on micro needles in PolyEthylene (Glycol). The first for the drugs delivery includes a membrane whose optical reflected wavelength is related to the concentration of drug. Here, we present our preliminary result in diffusion of drugs between the membrane and the microneedles. The second device is gold coated and it works as electrode for the electrochemical detection of species in the interstitial fluid. A preliminary result in detection of glucose will be shown.

Paper Details

Date Published: 1 June 2015
PDF: 6 pages
Proc. SPIE 9518, Bio-MEMS and Medical Microdevices II, 95180L (1 June 2015); doi: 10.1117/12.2178919
Show Author Affiliations
P. Dardano, IMM, CNR (Italy)
IMAST Scarl (Italy)
A. Caliò, IMM, CNR (Italy)
IMAST Scarl (Italy)
Univ. degli Studi di Napoli Federico II (Italy)
J. Politi, IMM, CNR (Italy)
IMAST Scarl (Italy)
Univ. degli Studi di Napoli Federico II (Italy)
V. Di Palma, IMAST Scarl (Italy)
ST Microelectronics (Italy)
M. F. Bevilacqua, IMAST Scarl (Italy)
ST Microelectronics (Italy)
I. Rea, IMM, CNR (Italy)
IMAST Scarl (Italy)
M. Casalino, IMM, CNR (Italy)
IMAST Scarl (Italy)
A. Di Matteo, IMAST Scarl (Italy)
ST Microelectronics (Italy)
I. Rendina, IMM, CNR (Italy)
IMAST Scarl (Italy)
L. De Stefano, IMM, CNR (Italy)
IMAST Scarl (Italy)


Published in SPIE Proceedings Vol. 9518:
Bio-MEMS and Medical Microdevices II
Sander van den Driesche, Editor(s)

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