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Proceedings Paper

Piezoelectric sensors for use as a DNA probe
Author(s): James G. Tsacoyeanes
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Paper Abstract

It will be shown that a quartz crystal coated with single strand DNA can act as a sensor for hybridization in liquids. The method used is based on the change in oscillating frequency resulting from the increase in mass on the crystal surface which is accompanying the hybridization. Specifically, it will be shown how an AT - cut quartz crystal oscillating at 5 MHz would operate as a DNA probe. Also a theoretical model will be presented which will show what the key physical parameters are, their interrelationships as well as their effect on measuring the inimobilization of DNA on a piezoelectric crystal.

Paper Details

Date Published: 1 October 1990
PDF: 10 pages
Proc. SPIE 1307, Electro-Optical Materials for Switches, Coatings, Sensor Optics, and Detectors, (1 October 1990); doi: 10.1117/12.21646
Show Author Affiliations
James G. Tsacoyeanes, Hughes Danbury Optical Systems, Inc. (United States)

Published in SPIE Proceedings Vol. 1307:
Electro-Optical Materials for Switches, Coatings, Sensor Optics, and Detectors
Rudolf Hartmann; M. J. Soileau; Vijay K. Varadan, Editor(s)

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