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Proceedings Paper

Optical imaging in turbid media using early arriving photons
Author(s): Lev T. Perelman; Jun Wu; Irving Itzkan; Yang Wang; Ramachandra R. Dasari; Michael S. Feld
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Paper Abstract

We present theoretical and experimental work on time resolved photon migration using short pulse laser radiation. The significant information about structure of turbid tissue is carried by the early arriving photons that follow almost straight arrival and return paths to the detected object in the tissue. The diffusion approximation to the transport equation in tissue does not provide a satisfactory solution for this regime, because the earliest photons are not sufficiently randomized in media in which the phase function is highly anisotropic. We are using a path integral technique to model this regime. The experiments use a short pulse Ti:sapphire laser and streak camera to obtain time resolved photon migration data from phantom samples. Our results show that a theory based on path integral calculation agrees with experimental data better than does the diffusion approximation. The thoery based on path integral calculation agrees with experimental data better than does the diffusion approximation. The theory can be used to interpret the experimental data and obtain optical imaging through turbid media.

Paper Details

Date Published: 30 May 1995
PDF: 6 pages
Proc. SPIE 2389, Optical Tomography, Photon Migration, and Spectroscopy of Tissue and Model Media: Theory, Human Studies, and Instrumentation, (30 May 1995); doi: 10.1117/12.209972
Show Author Affiliations
Lev T. Perelman, Massachusetts Institute of Technology (United States)
Jun Wu, Massachusetts Institute of Technology (United States)
Irving Itzkan, Massachusetts Institute of Technology (United States)
Yang Wang, Massachusetts Institute of Technology (United States)
Ramachandra R. Dasari, Massachusetts Institute of Technology (United States)
Michael S. Feld, Massachusetts Institute of Technology (United States)


Published in SPIE Proceedings Vol. 2389:
Optical Tomography, Photon Migration, and Spectroscopy of Tissue and Model Media: Theory, Human Studies, and Instrumentation
Britton Chance; Robert R. Alfano, Editor(s)

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