Share Email Print
cover

Proceedings Paper

Analytical perturbation theory of photon migration in the presence of a single absorbing or scattering defect sphere
Author(s): Shechao Charles Feng; Fanan Zeng; Britton Chance
Format Member Price Non-Member Price
PDF $14.40 $18.00
cover GOOD NEWS! Your organization subscribes to the SPIE Digital Library. You may be able to download this paper for free. Check Access

Paper Abstract

We present an analytical perturbation analysis to study the sensitivity of diffusive photon flux to the addition of a small spherical defect object in turbid multiple scattering media such as human tissue. As a first simple application of this perturbation theory, we derive analytically the photon migration path distribution function for both the infinite medium and the semi- infinite medium geometries. This allows one to write down analytical expressions of the shape and size of the so-called 'banana' region in which the photon migration paths are concentrated. We then derive analytically the sensitivity of detected photon flux densities to the inclusion of a small spherical defect in a turbid tissue medium, for both continuous wave (cw) and frequency modulation conditions, and arbitrary contrast between the optical parameters of the defect sphere and those of the surrounding medium.

Paper Details

Date Published: 30 May 1995
PDF: 10 pages
Proc. SPIE 2389, Optical Tomography, Photon Migration, and Spectroscopy of Tissue and Model Media: Theory, Human Studies, and Instrumentation, (30 May 1995); doi: 10.1117/12.209946
Show Author Affiliations
Shechao Charles Feng, Univ. of California/Los Angeles (United States)
Fanan Zeng, Univ. of California/Los Angeles (United States)
Britton Chance, Univ. of Pennsylvania (United States)


Published in SPIE Proceedings Vol. 2389:
Optical Tomography, Photon Migration, and Spectroscopy of Tissue and Model Media: Theory, Human Studies, and Instrumentation
Britton Chance; Robert R. Alfano, Editor(s)

© SPIE. Terms of Use
Back to Top