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Proceedings Paper

Three month follow-up of changes in the rabbit cornea after photoablation with a pulsed scanning beam at 213 nm
Author(s): Per G. Soederberg; Takaaki Matsui; Fabrice Manns; Jin-Hui Shen; Jean-Marie A. Parel; Jean-Marc Legeais; Michele Savoldelli; Isabelle Drubaix; Maurice Menashe; Gilles Renard; Yves Pouliquen
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Paper Abstract

A scanning beam of nano-second pulses at 213 nm flattens the cornea as predicted. However, there is a considerable variability in the flattening and the ablation is not safe. Ablation for 16 D flattening with an active spot overlap of 50% induced 8.9 +/- 5.3 D (n equals 7) as measured by the TMS topography system (ring 7 average) and 5.8 +/- 4.1 D (n equals 5) as measured with the SK-1 (2 mm zone) system. Ablation for 6 D flattening with an active spot overlap of 70% induced approximately 2 D flattening to 2 D steepening (n equals 3) as measured with the TMS (ring 7) and 6.6 +/- 4.33 D (n equals 7) flattening as measured by SK-1 (2 mm zone) keratometry. There was no change in IOP at 12 weeks after as compared to before ablation. There was a net increase of central and peripheral corneal thickness at 12 weeks after the ablation as compared to preoperatively. Epithelial defects remained up to 4 weeks after ablation. After four weeks, vessels had invaded the cornea in 30% of the cases and remained throughout the three months observed. It is concluded that 213 nm nano-second pulses can be used for flattening the cornea but the system should not be used for clinical trials in humans until the adverse effects can be avoided.

Paper Details

Date Published: 22 May 1995
PDF: 6 pages
Proc. SPIE 2393, Ophthalmic Technologies V, (22 May 1995); doi: 10.1117/12.209869
Show Author Affiliations
Per G. Soederberg, Bascom Palmer Eye Institute/Univ. of Miami School of Medicine (United States)
Karolinska Institutet (Sweden)
Takaaki Matsui, Bascom Palmer Eye Institute/Univ. of Miami School of Medicine (United States)
Fabrice Manns, Bascom Palmer Eye Institute/Univ. of Miami School of Medicine (United States)
Jin-Hui Shen, Bascom Palmer Eye Institute/Univ. of Miami School of Medicine (United States)
Jean-Marie A. Parel, Bascom Palmer Eye Institute/Univ. of Miami School of Medicine (United States)
Univ. de Paris Hopital de l'Hotel-Dieu (France)
Jean-Marc Legeais, Univ. de Paris Hopital de l'Hotel-Dieu (France)
Michele Savoldelli, Univ. de Paris Hopital de l'Hotel-Dieu (France)
Isabelle Drubaix, Univ. de Paris Hopital de l'Hotel-Dieu (France)
Maurice Menashe, Univ. de Paris Hopital de l'Hotel-Dieu (France)
Gilles Renard, Univ. de Paris Hopital de l'Hotel-Dieu (France)
Yves Pouliquen, Univ. de Paris Hopital de l'Hotel-Dieu (France)


Published in SPIE Proceedings Vol. 2393:
Ophthalmic Technologies V
Jean-Marie Parel; Qiushi Ren; Karen Margaret Joos, Editor(s)

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