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Proceedings Paper

Treatment of skin melanomas with the use of pulsed laser radiation
Author(s): Konstantin G. Moskalik M.D.; Robert I. Wagner; Alexander P. Kozlov
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Paper Abstract

The strong pulsed lasers radiation on the Neodim glass was used for the treatment of 265 patients with stage I skin melanoma. To 230 (86.4%) of them the treatment was carried out 5 years ago and even earlier. The duration of follow-up was from 1 to 22 years. The local recurrence of melanoma was diagnosed in 2 (0.75%) of these patients. Regional metastases developed in 44 (16.6%) patients, distant metastases--in 12 (4.5%) patients; in 1 (0.4%) patient the transport metastasis was revealed. More over, in patients to whom this type of treatment was carried out 5 years ago and even earlier regional metastases were diagnosed in 19.1% of cases, distant metastases--in 5.2% of cases, and transport metastases--in 0.4% of cases. 5-year survival rate of the patients made up 83.2%. In case of the I level of invasion (according to Clark classification) 100% of patients were alive for 5 years and even longer, in case of the II level of invasion this index made up 92.3%, in case of the III level--85.7%, and in case of the IV level--80.5%. In melanomas the thickness of which did not exceed 1.5 mm (according to Breslow classification) 5-year survival rate of the patients made up 96.7%, and in the tumors being from 1.51 mm to 4.5 mm thick this index mae up 80.0%. The strong pulsed lasers radiation is the effective method of treatment of plane or slightly elevated skin melanomas of the I-IV levels of invasion (Clark classification) the thickness of which is up to 4.5 mm according to Breslow.

Paper Details

Date Published: 12 May 1995
PDF: 6 pages
Proc. SPIE 2395, Lasers in Surgery: Advanced Characterization, Therapeutics, and Systems V, (12 May 1995); doi: 10.1117/12.209148
Show Author Affiliations
Konstantin G. Moskalik M.D., N.N. Petrov Research Institute of Oncology (Russia)
Robert I. Wagner, N.N. Petrov Research Institute of Oncology (Russia)
Alexander P. Kozlov, N.N. Petrov Research Institute of Oncology (Russia)


Published in SPIE Proceedings Vol. 2395:
Lasers in Surgery: Advanced Characterization, Therapeutics, and Systems V
R. Rox Anderson M.D.; Graham M. Watson M.D.; Rudolf W. Steiner; Douglas E. Johnson M.D.; Stanley M. Shapshay M.D.; Michail M. Pankratov; George S. Abela M.D.; Lawrence S. Bass M.D.; John V. White M.D.; Rodney A. White M.D.; Kenneth Eugene Bartels D.V.M.; Lloyd P. Tate V.D.M.; C. Thomas Vangsness M.D., Editor(s)

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