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Proceedings Paper

Near infrared radiation damage mechanism in the lens
Author(s): Per G. Söderberg; Nooshin Talebizadeh; Konstantin Galichanin; Martin Kronschläger; Karl Schulmeister; Zhaohua Yu
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Paper Abstract

The current data strongly indicates that there is no photochemical effect of in vivo exposure to 1090 nm near IRR radiation within the pupil. Four groups of 20 Sprague-Dawley rats were unilaterally exposed in vivo to 96 W·cm-2 centered inside the pupil for 10, 18, 33 and 60 min, respectively depending on group belonging. This resulted in radiant exposure doses of 57, 103, 198 and 344 kJ·cm-2. Temperature evolution at the limbus during the exposure and difference of intensity of forward light scattering between the exposed and the contralateral not exposed eye was measured at 1 week after exposure. The temperature at the limbus was found to increase exponentially towards an asymptote with an asymptote temperature of around 7 °C and a time constant (1/k) of around 15 s. No increase of light scattering was found despite that the cumulated radiant exposure dose was [80;250] times the threshold for photochemically induced cataract suggested by previous empirical data. It is concluded that at 1090 nm near IRR there is no photochemical effect.

Paper Details

Date Published: 20 March 2015
PDF: 5 pages
Proc. SPIE 9307, Ophthalmic Technologies XXV, 930717 (20 March 2015); doi: 10.1117/12.2086661
Show Author Affiliations
Per G. Söderberg, Uppsala Univ. (Sweden)
Nooshin Talebizadeh, Uppsala Univ. (Sweden)
Konstantin Galichanin, Uppsala Univ. (Sweden)
Martin Kronschläger, Uppsala Univ. (Sweden)
Karl Schulmeister, Seibersdorf Labor GmbH (Austria)
Zhaohua Yu, Uppsala Univ. (Sweden)

Published in SPIE Proceedings Vol. 9307:
Ophthalmic Technologies XXV
Fabrice Manns; Per G. Söderberg; Arthur Ho, Editor(s)

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