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Proceedings Paper

Brief review on the effect of low-power laser irradiation on neutrophils with emphasis on emerging fungal infections
Author(s): F. F. Sperandio; G. M. A. C. Bani; A. C. S. C. Mendes; M. R. P. L. Brigagão; G. B. Santos; L. C. C. Malaquias; J. K. Chavasco; L. M. Verinaud; E. Burger
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Paper Abstract

Polymorphonuclear neutrophils (PMN) participate in an active way in the innate immunity developed after the fungal infection paracoccidioidomycosis (PCM). Nevertheless, the sole participation of neutrophils is not sufficient to eradicate PCM`s pathogenic fungus: Paracoccidioides brasiliensis (Pb). In that way, we aimed to develop a treatment capable of stimulating PMN to the site of injury through low-level laser therapy (LLLT). (LLLT) is safe to use and has not been linked to microorganism resistance so far; in addition, based on previous studies we understand that LLLT may be useful to treat several medical conditions through the stimulation and activation of certain types of cells. This brief review is based on the novel attempt of activating PMN against a fungal infection.

Paper Details

Date Published: 5 March 2015
PDF: 9 pages
Proc. SPIE 9309, Mechanisms for Low-Light Therapy X, 93090L (5 March 2015); doi: 10.1117/12.2083138
Show Author Affiliations
F. F. Sperandio, Federal Univ. of Alfenas (Brazil)
G. M. A. C. Bani, Federal Univ. of Alfenas (Brazil)
A. C. S. C. Mendes, Federal Univ. of Alfenas (Brazil)
M. R. P. L. Brigagão, Federal Univ. of Alfenas (Brazil)
G. B. Santos, Federal Univ. of Alfenas (Brazil)
L. C. C. Malaquias, Federal Univ. of Alfenas (Brazil)
J. K. Chavasco, Federal Univ. of Alfenas (Brazil)
L. M. Verinaud, State Univ. of Campinas (Brazil)
E. Burger, Federal Univ. of Alfenas (Brazil)


Published in SPIE Proceedings Vol. 9309:
Mechanisms for Low-Light Therapy X
Michael R. Hamblin; James D. Carroll; Praveen Arany, Editor(s)

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