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Proceedings Paper

Validation of TMJ osteoarthritis synthetic defect database via non-rigid registration
Author(s): Beatriz Paniagua; Juliette Pera; Francois Budin; Liliane Rosas Gomes; Martin A. Styner; Lucia H. S. Cevidanes; Tung Nguyen
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Paper Abstract

Temporomandibular joint (TMJ) disorders are a group of conditions that cause pain and dysfunction in the jaw joint and the muscles controlling jaw movement. However, diagnosis and treatment of these conditions remain controversial. To date, there is no single sign, symptom, or test that can clearly diagnose early stages of osteoarthritis (OA). Instead, the diagnosis is based on a consideration of several factors, including radiological evaluation. The current radiological diagnosis scores of TMJ pathology are subject to misdiagnosis. We believe these scores are limited by the acquisition procedures, such as oblique cuts of the CT and head positioning errors, and can lead to incorrect diagnoses of flattening of the head of the condyle, formation of osteophytes, or condylar pitting. This study consists of creating and validating a methodological framework to simulate defects in CBCT scans of known location and size, in order to create synthetic TMJ OA database. User-generated defects were created using a non-rigid deformation protocol in CBCT. All segmentation evaluation, surface distances and linear distances from the user-generated to the simulated defects showed our methodological framework to be very precise and within a voxel (0.5 mm) of magnitude. A TMJ OA synthetic database will be created next, and evaluated by expert radiologists, and this will serve to evaluate how sensitive the current radiological diagnosis tools are.

Paper Details

Date Published: 17 March 2015
PDF: 6 pages
Proc. SPIE 9417, Medical Imaging 2015: Biomedical Applications in Molecular, Structural, and Functional Imaging, 94171C (17 March 2015); doi: 10.1117/12.2081983
Show Author Affiliations
Beatriz Paniagua, The Univ. of North Carolina at Chapel Hill (United States)
Juliette Pera, The Univ. of North Carolina at Chapel Hill (United States)
Francois Budin, The Univ. of North Carolina at Chapel Hill (United States)
Liliane Rosas Gomes, Univ. of Michigan, School of Dentistry (United States)
Martin A. Styner, The Univ. of North Carolina at Chapel Hill (United States)
Lucia H. S. Cevidanes, Univ. of Michigan, School of Dentistry (United States)
Tung Nguyen, The Univ. of North Carolina at Chapel Hill (United States)


Published in SPIE Proceedings Vol. 9417:
Medical Imaging 2015: Biomedical Applications in Molecular, Structural, and Functional Imaging
Barjor Gimi; Robert C. Molthen, Editor(s)

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