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Proceedings Paper

Performance comparison of breast imaging modalities using a 4AFC human observer study
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Paper Abstract

This work compares the visibility of spheres and simulated masses in 2D-mammography and tomosynthesis systems using human observer studies. Performing comparison studies between breast imaging systems poses a number of practical challenges within a clinical environment. We therefore adopted a simulation approach which included synthetic breast blocks, a validated lesion simulation model and a set of validated image modelling tools as a viable alternative to clinical trials. A series of 4-alternative forced choice (4AFC) human observer experiments has been conducted for signal detection tasks using masses and spheres as targets. Five physicists participated in the study viewing images with a 5mm target at a range of contrast levels and 60 trials per experimental condition. The results showed that tomosynthesis has a lower threshold contrast than 2D-mammography for masses and spheres, and that detection studies using spheres may produce overly-optimistic threshold contrast values.

Paper Details

Date Published: 18 March 2015
PDF: 7 pages
Proc. SPIE 9412, Medical Imaging 2015: Physics of Medical Imaging, 94121T (18 March 2015); doi: 10.1117/12.2081878
Show Author Affiliations
Premkumar Elangovan, Univ. of Surrey (United Kingdom)
Alaleh Rashidnasab, Univ. of Surrey (United Kingdom)
Univ. Hospitals Leuven (Belgium)
Alistair Mackenzie, The Royal Surrey County Hospital NHS Trust (United Kingdom)
Univ. of Surrey (United Kingdom)
David R. Dance, The Royal Surrey County Hospital NHS Trust (United Kingdom)
Univ. of Surrey (United Kingdom)
Kenneth C. Young, The Royal Surrey County Hospital NHS Trust (United Kingdom)
Univ. of Surrey (United Kingdom)
Hilde Bosmans, Univ. Hospitals Leuven (Belgium)
William P. Segars, Duke Univ. (United States)
Kevin Wells, Univ. of Surrey (United Kingdom)


Published in SPIE Proceedings Vol. 9412:
Medical Imaging 2015: Physics of Medical Imaging
Christoph Hoeschen; Despina Kontos, Editor(s)

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