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Proceedings Paper

A novel approach to motion correction for ASL images based on brain contours
Author(s): Giacomo Tarroni; Marco Castellaro; Carlo Boffano; Maria Grazia Bruzzone; Alessandra Bertoldo; Enrico Grisan
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Paper Abstract

Motion correction in Arterial Spin Labeling (ASL) is essential to accurately assess brain perfusion. Motion correction techniques are usually based on intensity-related information, which might be unreliable in ASL due to local intensity differences between control and labeled acquisitions and to non-uniform volume magnetization caused by background-suppressed acquisition protocols. Accordingly, a novel motion correction technique based only on brain contour points is presented and tested against a widely used intensity-based technique (MCFLIRT). The proposed Contour-Based Motion Correction (CBCM) technique relies on image segmentation (to extract brain contour point clouds) and on Iterative Closest Point algorithm (to estimate the roto-translation required to align them). At variance with other approaches based on point clouds alignment, the local 3D curvature is also computed for each contour point and used as an additional coordinate to increase the accuracy of the alignment. The technique has been tested along with MCFLIRT on a database of randomly roto-translated brain volumes. Several error metrics have been computed and compared between the two techniques. The results show that the proposed technique is able to achieve a higher accuracy than MCFLIRT without any intensity-dependent information.

Paper Details

Date Published: 17 March 2015
PDF: 6 pages
Proc. SPIE 9417, Medical Imaging 2015: Biomedical Applications in Molecular, Structural, and Functional Imaging, 94171U (17 March 2015); doi: 10.1117/12.2081784
Show Author Affiliations
Giacomo Tarroni, Univ. degli Studi di Padova (Italy)
Marco Castellaro, Univ. degli Studi di Padova (Italy)
Carlo Boffano, Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta (Italy)
Maria Grazia Bruzzone, Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta (Italy)
Alessandra Bertoldo, Univ. degli Studi di Padova (Italy)
Enrico Grisan, Univ. degli Studi di Padova (Italy)


Published in SPIE Proceedings Vol. 9417:
Medical Imaging 2015: Biomedical Applications in Molecular, Structural, and Functional Imaging
Barjor Gimi; Robert C. Molthen, Editor(s)

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