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Proceedings Paper

Diode laser systems for photodynamic therapy
Author(s): William A. Papworth; W. L. Mitchell; Dale D. Severson; Jon A. Warner; Greg B. Rocklin; Greta M. Garbo; Daniel R. Doiron
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Paper Abstract

AlGaInP diode lasers generate optical output in a range of the spectrum suitable for the activation of several second=generation photosensitizers including tin ethyl etiopurpurin, SnET2. The development of a system suitable for this application entails coupling the output of multiple highly divergent and astigmatic sources into a single optical fiber for most applications. Various methods of fulfilling this requirement will be discussed along with the advantages and drawbacks of each method. The incorporation into the clinical laser system of on-line dosimetry control of the light delivery parameters will be described along with the results of biological equivalency studies.

Paper Details

Date Published: 1 May 1995
PDF: 8 pages
Proc. SPIE 2392, Optical Methods for Tumor Treatment and Detection: Mechanisms and Techniques in Photodynamic Therapy IV, (1 May 1995); doi: 10.1117/12.208174
Show Author Affiliations
William A. Papworth, PDT Systems, Inc. (United States)
W. L. Mitchell, PDT Systems, Inc. (United States)
Dale D. Severson, PDT Systems, Inc. (United States)
Jon A. Warner, PDT Systems, Inc. (United States)
Greg B. Rocklin, PDT Pharmaceuticals, Inc. (United States)
Greta M. Garbo, PDT Pharmaceuticals, Inc. (United States)
Daniel R. Doiron, PDT Systems, Inc. (United States)


Published in SPIE Proceedings Vol. 2392:
Optical Methods for Tumor Treatment and Detection: Mechanisms and Techniques in Photodynamic Therapy IV
Thomas J. Dougherty, Editor(s)

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