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Proceedings Paper

Investigating the geometry of pig airways using computed tomography
Author(s): Hansen A. Mansy; Md Khurshidul Azad; Brandon McMurray; Brian Henry; Thomas J. Royston; Richard H. Sandler
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Paper Abstract

Numerical modeling of sound propagation in the airways requires accurate knowledge of the airway geometry. These models are often validated using human and animal experiments. While many studies documented the geometric details of the human airways, information about the geometry of pig airways is scarcer. In addition, the morphology of animal airways can be significantly different from that of humans. The objective of this study is to measure the airway diameter, length and bifurcation angles in domestic pigs using computed tomography. After imaging the lungs of 3 pigs, segmentation software tools were used to extract the geometry of the airway lumen. The airway dimensions were then measured from the resulting 3 D models for the first 10 airway generations. Results showed that the size and morphology of the airways of different animals were similar. The measured airway dimensions were compared with those of the human airways. While the trachea diameter was found to be comparable to the adult human, the diameter, length and branching angles of other airways were noticeably different from that of humans. For example, pigs consistently had an early airway branching from the trachea that feeds the superior (top) right lung lobe proximal to the carina. This branch is absent in the human airways. These results suggested that the human geometry may not be a good approximation of the pig airways and may contribute to increasing the errors when the human airway geometric values are used in computational models of the pig chest.

Paper Details

Date Published: 17 March 2015
PDF: 7 pages
Proc. SPIE 9417, Medical Imaging 2015: Biomedical Applications in Molecular, Structural, and Functional Imaging, 94172N (17 March 2015); doi: 10.1117/12.2081552
Show Author Affiliations
Hansen A. Mansy, Univ. of Central Florida (United States)
Md Khurshidul Azad, Univ. of Central Florida (United States)
Brandon McMurray, Univ. of Central Florida (United States)
Brian Henry, Univ. of Illinois at Chicago (United States)
Thomas J. Royston, Univ. of Illinois at Chicago (United States)
Richard H. Sandler, Nemours Childrens Hospital (United States)


Published in SPIE Proceedings Vol. 9417:
Medical Imaging 2015: Biomedical Applications in Molecular, Structural, and Functional Imaging
Barjor Gimi; Robert C. Molthen, Editor(s)

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