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Proceedings Paper

Block copolymers encapsulated poly (aryl benzyl ether) dendrimer silicon (IV) phthalocyanine for in vivo and in vitro photodynamic efficacy of choroidal neovascularization
Author(s): Xiongwei Wang; Kuizhi Chen; Zheng Huang; Yiru Peng
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Paper Abstract

A novel series of poly (aryl benzyl ether) dendrimer silicon phthalocyanines loaded block copolymers ethoxypoly(ethylene glycol)-poly (lactic-co-glycolic acid) (MPEG-PLGA)were formed. The time-dependent intracellular uptake of nanoparticles in HUVECs cells increased as they were incorporated into nanoparticles. With its highly effective selective accumulation on choroidal neovascularization(CNV). This treatment resulted in a efficacious choroidal neovascularization (CNV) occlusion with minimal unfavorable phototoxicity.

Paper Details

Date Published: 2 March 2015
PDF: 4 pages
Proc. SPIE 9308, Optical Methods for Tumor Treatment and Detection: Mechanisms and Techniques in Photodynamic Therapy XXIV, 93080L (2 March 2015); doi: 10.1117/12.2081532
Show Author Affiliations
Xiongwei Wang, Fujian Normal Univ. (China)
Kuizhi Chen, Fujian Normal Univ. (China)
Zheng Huang, Fujian Normal Univ. (China)
Yiru Peng, Fujian Normal Univ. (China)


Published in SPIE Proceedings Vol. 9308:
Optical Methods for Tumor Treatment and Detection: Mechanisms and Techniques in Photodynamic Therapy XXIV
David H. Kessel; Tayyaba Hasan, Editor(s)

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