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Proceedings Paper

Cadaveric in-situ testing of optical coherence tomography system-based skull base surgery guidance
Author(s): Cuiru Sun; Osaama H. Khan; Peter Siegler; Jamil Jivraj; Ronnie Wong; Victor X. D. Yang
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Paper Abstract

Optical Coherence Tomography (OCT) has extensive potential for producing clinical impact in the field of neurological diseases. A neurosurgical OCT hand-held forward viewing probe in Bayonet shape has been developed. In this study, we test the feasibility of integrating this imaging probe with modern navigation technology for guidance and monitoring of skull base surgery. Cadaver heads were used to simulate relevant surgical approaches for treatment of sellar, parasellar and skull base pathology. A high-resolution 3D CT scan was performed on the cadaver head to provide baseline data for navigation. The cadaver head was mounted on existing 3- or 4-point fixation systems. Tracking markers were attached to the OCT probe and the surgeon-probe-OCT interface was calibrated. 2D OCT images were shown in real time together with the optical tracking images to the surgeon during surgery. The intraoperative video and multimodality imaging data set, consisting of real time OCT images, OCT probe location registered to neurosurgical navigation were assessed. The integration of intraoperative OCT imaging with navigation technology provides the surgeon with updated image information, which is important to deal with tissue shifts and deformations during surgery. Preliminary results demonstrate that the clinical neurosurgical navigation system can provide the hand held OCT probe gross anatomical localization. The near-histological imaging resolution of intraoperative OCT can improve the identification of microstructural/morphology differences. The OCT imaging data, combined with the neurosurgical navigation tracking has the potential to improve image interpretation, precision and accuracy of the therapeutic procedure.

Paper Details

Date Published: 26 March 2015
PDF: 5 pages
Proc. SPIE 9305, Optical Techniques in Neurosurgery, Neurophotonics, and Optogenetics II, 930507 (26 March 2015); doi: 10.1117/12.2080614
Show Author Affiliations
Cuiru Sun, Ryerson Univ. (Canada)
Tianjin Univ. (China)
Osaama H. Khan, Sunnybrook Health Sciences Ctr. (Canada)
Peter Siegler, Ryerson Univ. (Canada)
Jamil Jivraj, Ryerson Univ. (Canada)
Ronnie Wong, Ryerson Univ. (Canada)
Victor X. D. Yang, Ryerson Univ. (Canada)
Sunnybrook Health Sciences Ctr. (Canada)
Univ. of Toronto (Canada)


Published in SPIE Proceedings Vol. 9305:
Optical Techniques in Neurosurgery, Neurophotonics, and Optogenetics II
Henry Hirschberg; E. Duco Jansen; Samarendra K. Mohanty; Nitish V. Thakor; Qingming Luo; Steen J. Madsen, Editor(s)

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