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Proceedings Paper

Three-dimensional photoacoustic and ultrasonic endoscopic imaging of two rabbit esophagi
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Paper Abstract

The addition of photoacoustic endoscopy to conventional endoscopic ultrasound offers imaging capabilities that may improve diagnosis and clinical care of gastrointestinal tract diseases. In this study, using a 3.8-mm diameter dual-mode photoacoustic and ultrasonic endoscopic probe, we investigated photoacoustic and ultrasonic image features of rabbit esophagi. Specifically, we performed ex vivo imaging of intact rabbit esophagi and correlated the acquired images with histology. Without motion artifact-based limitations, we were able to utilize the full resolving power of the endoscopic device and acquire the first three-dimensional vasculature map of the esophagus and mediastinum, along with coregistered tissue density information. Here, we present the experimental results and discuss potential clinical applications of the technique.

Paper Details

Date Published: 11 March 2015
PDF: 8 pages
Proc. SPIE 9323, Photons Plus Ultrasound: Imaging and Sensing 2015, 932334 (11 March 2015); doi: 10.1117/12.2080294
Show Author Affiliations
Joon-Mo Yang, Washington Univ. in St. Louis (United States)
Christopher P. Favazza, Washington Univ. in St. Louis (United States)
Mayo Clinic (United States)
Junjie Yao, Washington Univ. in St. Louis (United States)
Ruimin Chen, Univ. of Southern California (United States)
Qifa Zhou, Univ. of Southern California (United States)
K. Kirk Shung, Univ. of Southern California (United States)
Lihong V. Wang, Washington Univ. in St. Louis (United States)


Published in SPIE Proceedings Vol. 9323:
Photons Plus Ultrasound: Imaging and Sensing 2015
Alexander A. Oraevsky; Lihong V. Wang, Editor(s)

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