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Proceedings Paper

Image-guided surgery using near-infrared fluorescent light: from bench to bedside
Author(s): Leonora S. F. Boogerd; Henricus J. M. Handgraaf; Cornelis J. H. van de Velde; Alexander L. Vahrmeijer
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Paper Abstract

Due to its relatively high tissue penetration, near-infrared (NIR; 700-900 nm) fluorescent light has the potential to visualize structures that need to be resected (e.g. tumors, lymph nodes) and structures that need to be spared (e.g. nerves, ureters, bile ducts). Until now, most clinical trials have focused on suboptimal, non-targeted dyes. Although successful, a new era in image-guided surgery has begun by the introduction of tumor-targeted agents. In this paper, we will describe how tumor-targeted NIR fluorescent imaging can be applied in a clinical setting.

Paper Details

Date Published: 4 March 2015
PDF: 11 pages
Proc. SPIE 9311, Molecular-Guided Surgery: Molecules, Devices, and Applications, 93110U (4 March 2015); doi: 10.1117/12.2079762
Show Author Affiliations
Leonora S. F. Boogerd, Leiden Univ. Medical Ctr. (Netherlands)
Henricus J. M. Handgraaf, Leiden Univ. Medical Ctr. (Netherlands)
Cornelis J. H. van de Velde, Leiden Univ. Medical Ctr. (Netherlands)
Alexander L. Vahrmeijer, Leiden Univ. Medical Ctr. (Netherlands)

Published in SPIE Proceedings Vol. 9311:
Molecular-Guided Surgery: Molecules, Devices, and Applications
Brian W. Pogue; Sylvain Gioux, Editor(s)

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