Share Email Print
cover

Proceedings Paper

Dynamic diffuse optical tomography for assessing changes of breast tumors during neoadjuvant chemotherapy
Author(s): Jacqueline E. Gunther; Emerson Lim; Hyun Keol Kim; Mindy Brown; Susan Refice; Kevin Kalinsky; Dawn Hershman; Andreas H. Hielscher
Format Member Price Non-Member Price
PDF $14.40 $18.00
cover GOOD NEWS! Your organization subscribes to the SPIE Digital Library. You may be able to download this paper for free. Check Access

Paper Abstract

We have developed a dynamic diffuse optical tomography imaging system that is capable of 3D imaging of both breasts simultaneously. In an ongoing study subjects receiving neoadjuvant chemotherapy are imaged at 6 time points throughout their 5-month treatment. At each time point the subjects preform a breath hold to observe the hemodynamic effects in the breasts. For each session the percent change of various hemodynamic parameters during the breath hold is determined. Preliminary results from show statistically significant differences in washout rates and deoxyhemoglobin changes at the 2-week imaging point between subjects that respond and do not respond to treatment.

Paper Details

Date Published: 12 March 2015
PDF: 4 pages
Proc. SPIE 9319, Optical Tomography and Spectroscopy of Tissue XI, 93190C (12 March 2015); doi: 10.1117/12.2079435
Show Author Affiliations
Jacqueline E. Gunther, Columbia Univ. (United States)
Emerson Lim, Columbia Univ. (United States)
Hyun Keol Kim, Columbia Univ. (United States)
Mindy Brown, Herbert Irving Comprehensive Cancer Ctr. (United States)
Susan Refice, Herbert Irving Comprehensive Cancer Ctr. (United States)
Kevin Kalinsky, Columbia Univ. (United States)
Herbert Irving Comprehensive Cancer Ctr. (United States)
Dawn Hershman, Columbia Univ. (United States)
Herbert Irving Comprehensive Cancer Ctr. (United States)
Mailman School of Public Health (United States)
Andreas H. Hielscher, Columbia Univ. (United States)
Herbert Irving Comprehensive Cancer Ctr. (United States)


Published in SPIE Proceedings Vol. 9319:
Optical Tomography and Spectroscopy of Tissue XI
Bruce J. Tromberg; Arjun G. Yodh; Eva Marie Sevick-Muraca; Robert R. Alfano, Editor(s)

© SPIE. Terms of Use
Back to Top