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Proceedings Paper

Clinical trials in near infrared fluorescence imaging with IRDye 800CW
Author(s): Daniel R. Draney
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Paper Abstract

A monofunctional, heptamethine dye, IRDye® 800CW, is being manufactured under GMP conditions for use in human clinical trials. When attached to a suitable targeting agent and paired with an appropriate camera system, the dye allows Near Infrared (NIR) fluorescence imaging of tumor tissue during surgery. The talk will describe the properties of the dye and give an overview of current and planned clinical trials in Europe and the USA. The dye is available in both the NHS ester and carboxylate forms for conjugation to targeting molecules. A GMP toxicology study of the dye was described in a previous publication.

Paper Details

Date Published: 4 March 2015
PDF: 7 pages
Proc. SPIE 9311, Molecular-Guided Surgery: Molecules, Devices, and Applications, 93110L (4 March 2015); doi: 10.1117/12.2079285
Show Author Affiliations
Daniel R. Draney, LI-COR Biosciences (United States)


Published in SPIE Proceedings Vol. 9311:
Molecular-Guided Surgery: Molecules, Devices, and Applications
Brian W. Pogue; Sylvain Gioux, Editor(s)

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