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Proceedings Paper

Numerical modeling of photon migration in the cerebral cortex of the living rat using the radiative transport equation
Author(s): Hiroyuki Fujii; Shinpei Okawa; Ken Nadamoto; Eiji Okada; Yukio Yamada; Yoko Hoshi; Masao Watanabe
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Paper Abstract

Accurate modeling and efficient calculation of photon migration in biological tissues is requested for determination of the optical properties of living tissues by in vivo experiments. This study develops a calculation scheme of photon migration for determination of the optical properties of the rat cerebral cortex (ca 0.2 cm thick) based on the three-dimensional time-dependent radiative transport equation assuming a homogeneous object. It is shown that the time-resolved profiles calculated by the developed scheme agree with the profiles measured by in vivo experiments using near infrared light. Also, an efficient calculation method is tested using the delta-Eddington approximation of the scattering phase function.

Paper Details

Date Published: 10 March 2015
PDF: 6 pages
Proc. SPIE 9333, Biomedical Applications of Light Scattering IX, 933313 (10 March 2015); doi: 10.1117/12.2079265
Show Author Affiliations
Hiroyuki Fujii, Hokkaido Univ. (Japan)
Shinpei Okawa, National Defense Medical College (Japan)
Ken Nadamoto, Keio Univ. (Japan)
Eiji Okada, Keio Univ. (Japan)
Yukio Yamada, Univ. of Electro-Communications (Japan)
Yoko Hoshi, Tokyo Metropolitan Institute of Medical Science (Japan)
Masao Watanabe, Hokkaido Univ. (Japan)


Published in SPIE Proceedings Vol. 9333:
Biomedical Applications of Light Scattering IX
Adam Wax; Vadim Backman, Editor(s)

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