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Proceedings Paper

A portable and compact near-infrared spectral tomography system for predicting breast tumor response to neoadjuvant chemotherapy
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Paper Abstract

A portable hybrid frequency domain (FD)-continuous wave (CW) Near-Infrared spectroscopy NIRS system has been developed for quantifying changes in total hemoglobin, oxygen saturation and water content in the breast during neoadjuvant chemotherapy. Simultaneous acquisition of two sets of 3 FD channels and 3 CW channels could be completed within 1 min. System calibration and homogeneous phantom measurement show phase variation less than 3% when PMT gain from 0.7 to 1.1 was used. The study of integrating this system into the workflow of clinical oncology practice is ongoing.

Paper Details

Date Published: 5 March 2015
PDF: 6 pages
Proc. SPIE 9319, Optical Tomography and Spectroscopy of Tissue XI, 93190B (5 March 2015); doi: 10.1117/12.2079210
Show Author Affiliations
Yan Zhao, Dartmouth College (United States)
Fadi El-Ghussein, Dartmouth College (United States)
Ziqi Zhang, Dartmouth College (United States)
Brian W. Pogue, Dartmouth College (United States)
Keith D. Paulsen, Dartmouth College (United States)
Shudong Jiang, Dartmouth College (United States)


Published in SPIE Proceedings Vol. 9319:
Optical Tomography and Spectroscopy of Tissue XI
Bruce J. Tromberg; Arjun G. Yodh; Eva Marie Sevick-Muraca; Robert R. Alfano, Editor(s)

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