Share Email Print
cover

Proceedings Paper

In vivo optical elastography: stress and strain imaging of human skin lesions
Author(s): Shaghayegh Es'haghian; Peijun Gong; Kelsey M. Kennedy; Philip Wijesinghe; David D. Sampson; Robert A. McLaughlin; Brendan F. Kennedy
Format Member Price Non-Member Price
PDF $14.40 $18.00

Paper Abstract

Probing the mechanical properties of skin at high resolution could aid in the assessment of skin pathologies by, for example, detecting the extent of cancerous skin lesions and assessing pathology in burn scars. Here, we present two elastography techniques based on optical coherence tomography (OCT) to probe the local mechanical properties of skin. The first technique, optical palpation, is a high-resolution tactile imaging technique, which uses a complaint silicone layer positioned on the tissue surface to measure spatially-resolved stress imparted by compressive loading. We assess the performance of optical palpation, using a handheld imaging probe on a skin-mimicking phantom, and demonstrate its use on human skin. The second technique is a strain imaging technique, phase-sensitive compression OCE that maps depth-resolved mechanical variations within skin. We show preliminary results of in vivo phase-sensitive compression OCE on a human skin lesion.

Paper Details

Date Published: 6 March 2015
PDF: 8 pages
Proc. SPIE 9327, Optical Elastography and Tissue Biomechanics II, 93270C (6 March 2015); doi: 10.1117/12.2078706
Show Author Affiliations
Shaghayegh Es'haghian, The Univ. of Western Australia (Australia)
Peijun Gong, The Univ. of Western Australia (Australia)
Kelsey M. Kennedy, The Univ. of Western Australia (Australia)
Philip Wijesinghe, The Univ. of Western Australia (Australia)
David D. Sampson, The Univ. of Western Australia (Australia)
Robert A. McLaughlin, The Univ. of Western Australia (Australia)
Brendan F. Kennedy, The Univ. of Western Australia (Australia)


Published in SPIE Proceedings Vol. 9327:
Optical Elastography and Tissue Biomechanics II
Kirill V. Larin; David D. Sampson, Editor(s)

© SPIE. Terms of Use
Back to Top