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Proceedings Paper

Noninvasive 3D elasticity mapping using phase-stabilized optical coherence elastography
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Paper Abstract

We demonstrate a novel method for noninvasive elasticity mapping in three dimensions using phase stabilized swept source optical coherence elastography (PhS-SSOCE). By calculating the velocity in all radial directions from the origin of the induced shear wave, a volumetric elasticity map of the sample was generated. Due to the submicrometer spatial sensitivity of PhS-SSOCE, the loading force and the induced deformation amplitude can be minimal, thus preserving the structure and function of delicate tissues such as the cornea and sclera of the eye. Tissue mimicking agar phantoms were utilized for proof of concept testing and the results show that this method can noninvasively provide a three dimensional estimation of sample elasticity.

Paper Details

Date Published: 6 March 2015
PDF: 8 pages
Proc. SPIE 9327, Optical Elastography and Tissue Biomechanics II, 932703 (6 March 2015); doi: 10.1117/12.2078315
Show Author Affiliations
Manmohan Singh, Univ. of Houston (United States)
Jiasong Li, Univ. of Houston (United States)
Shang Wang, Baylor College of Medicine (United States)
Michael Twa, Univ. of Alabama at Birmingham (United States)
Kirill V. Larin, Univ. of Houston (United States)
Baylor College of Medicine (United States)

Published in SPIE Proceedings Vol. 9327:
Optical Elastography and Tissue Biomechanics II
Kirill V. Larin; David D. Sampson, Editor(s)

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