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Proceedings Paper

The influence of cellular uptake on the photostability and photoacoustic conversion efficiency of gold nanorods
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Paper Abstract

Their intense optical absorbance in the near-infrared window and chemical versatility make gold nanorods attractive for biomedical applications, such as photothermal therapies and photoacoustic imaging. However, their limited photostability remains a drawback of practical concern. In fact, when gold nanorods are irradiated with nanosecond laser pulses in resonance with their plasmon oscillations, there may occur reshaping into spherical particles or even fragmentation at higher optical fluences, which cause substantial modifications of their optical features with a loss of photoacoustic conversion efficiency. In this contribution, we focus on how the gold nanorods photostability is affected when these particles are modified for cellular uptake, by investigating their stability and photoacoustic conversion efficiency under near infrared pulsed irradiation at different laser fluences.

Paper Details

Date Published: 11 March 2015
PDF: 6 pages
Proc. SPIE 9323, Photons Plus Ultrasound: Imaging and Sensing 2015, 932346 (11 March 2015); doi: 10.1117/12.2077632
Show Author Affiliations
Lucia Cavigli, Istituto di Fisica Applicata Nello Carrara, CNR (Italy)
Fulvio Ratto, Istituto di Fisica Applicata Nello Carrara, CNR (Italy)
Francesca Tatini, Istituto di Fisica Applicata Nello Carrara, CNR (Italy)
Paolo Matteini, Istituto di Fisica Applicata Nello Carrara, CNR (Italy)
Alberto Cini, Istituto di Fisica Applicata Nello Carrara, CNR (Italy)
Ilaria Giovannelli, Univ. degli Studi di Firenze (Italy)
Marella de Angelis, Istituto di Fisica Applicata Nello Carrara, CNR (Italy)
Francesca Rossi, Istituto di Fisica Applicata Nello Carrara, CNR (Italy)
Sonia Centi, Istituto di Fisica Applicata Nello Carrara, CNR (Italy)
Roberto Pini, Istituto di Fisica Applicata Nello Carrara, CNR (Italy)


Published in SPIE Proceedings Vol. 9323:
Photons Plus Ultrasound: Imaging and Sensing 2015
Alexander A. Oraevsky; Lihong V. Wang, Editor(s)

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