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Proceedings Paper

First-harmonic sensitivity functions for a linearised diffusion model of ultrasound-modulated optical tomography
Author(s): Samuel Powell; Simon R. Arridge; Terence S. Leung
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Paper Abstract

Ultrasound-modulated optical tomography is an emerging biomedical imaging modality which uses the spatially localised acoustically-driven modulation of coherent light as a probe of the structure and optical properties of biological tissues. In this work we model the first-harmonic flux generated by the coupled physics using a simple linearised diffusion-style forward model. We derive analytical expressions for the sensitivity of this measurement type with respect to the optical absorption and scattering coefficients. These correlation measurement density functions can be employed as part of an image-reconstruction procedure capable of reconstructing quantitative images of the optical properties of a medium under investigation.

Paper Details

Date Published: 11 March 2015
PDF: 7 pages
Proc. SPIE 9323, Photons Plus Ultrasound: Imaging and Sensing 2015, 932342 (11 March 2015); doi: 10.1117/12.2077435
Show Author Affiliations
Samuel Powell, Univ. College London (United Kingdom)
Simon R. Arridge, Univ. College London (United Kingdom)
Terence S. Leung, Univ. College London (United Kingdom)

Published in SPIE Proceedings Vol. 9323:
Photons Plus Ultrasound: Imaging and Sensing 2015
Alexander A. Oraevsky; Lihong V. Wang, Editor(s)

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