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Proceedings Paper

In vivo melanoma depth detection by a handheld photoacoustic microscope
Author(s): Yong Zhou; Wenxin Xing; Konstantin I. Maslov; Lynn A. Cornelius; Lihong V. Wang
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Paper Abstract

We developed a handheld photoacoustic microscope (PAM) to detect melanoma and determine tumor depth in nude mice in vivo. Compared to our previous PAM system for melanoma imaging, a new light delivery mechanism is introduced to improve light penetration. We show that melanomas with 4.1 mm and 3.3 mm thicknesses can be successfully detected in phantom and in vivo experiments, respectively. With its deep melanoma imaging ability and novel handheld design, this system is promising for clinical melanoma diagnosis, prognosis, and surgical planning for patients at the bedside.

Paper Details

Date Published: 11 March 2015
PDF: 7 pages
Proc. SPIE 9323, Photons Plus Ultrasound: Imaging and Sensing 2015, 932304 (11 March 2015); doi: 10.1117/12.2076684
Show Author Affiliations
Yong Zhou, Washington Univ. in St. Louis (United States)
Wenxin Xing, Washington Univ. in St. Louis (United States)
Konstantin I. Maslov, Washington Univ. in St. Louis (United States)
Lynn A. Cornelius, Washington Univ. School of Medicine in St. Louis (United States)
Lihong V. Wang, Washington Univ. in St. Louis (United States)


Published in SPIE Proceedings Vol. 9323:
Photons Plus Ultrasound: Imaging and Sensing 2015
Alexander A. Oraevsky; Lihong V. Wang, Editor(s)

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