Share Email Print
cover

Proceedings Paper

In vivo deep brain imaging of rats using oral-cavity illuminated photoacoustic computed tomography
Author(s): Li Lin; Jun Xia; Terence T. W. Wong; Ruiying Zhang; Lihong V. Wang
Format Member Price Non-Member Price
PDF $14.40 $18.00
cover GOOD NEWS! Your organization subscribes to the SPIE Digital Library. You may be able to download this paper for free. Check Access

Paper Abstract

We demonstrate, by means of internal light delivery, photoacoustic imaging of the deep brain of rats in vivo. With fiber illumination via the oral cavity, we delivered light directly into the bottom of the brain, much more than can be delivered by external illumination. The study was performed using a photoacoustic computed tomography (PACT) system equipped with a 512-element full-ring transducer array, providing a full two-dimensional view aperture. Using internal illumination, the PACT system provided clear cross sectional photoacoustic images from the palate to the middle brain of live rats, revealing deep brain structures such as the hypothalamus, brain stem, and cerebral medulla.

Paper Details

Date Published: 11 March 2015
PDF: 5 pages
Proc. SPIE 9323, Photons Plus Ultrasound: Imaging and Sensing 2015, 93230G (11 March 2015); doi: 10.1117/12.2076482
Show Author Affiliations
Li Lin, Washington Univ. in St. Louis (United States)
Jun Xia, Washington Univ. in St. Louis (United States)
Univ. at Buffalo (United States)
Terence T. W. Wong, Washington Univ. in St. Louis (United States)
Ruiying Zhang, Washington Univ. in St. Louis (United States)
Lihong V. Wang, Washington Univ. in St. Louis (United States)


Published in SPIE Proceedings Vol. 9323:
Photons Plus Ultrasound: Imaging and Sensing 2015
Alexander A. Oraevsky; Lihong V. Wang, Editor(s)

© SPIE. Terms of Use
Back to Top