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Proceedings Paper

Optogenetics in animal model of alcohol addiction
Author(s): Maria Nalberczak; Kasia Radwanska
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Paper Abstract

Our understanding of the neuronal and molecular basis of alcohol addiction is still not satisfactory. As a consequence we still miss successful therapy of alcoholism. One of the reasons for such state is the lack of appropriate animal models which would allow in-depth analysis of biological basis of addiction. Here we will present our efforts to create the animal model of alcohol addiction in the automated learning device, the IntelliCage setup. Applying this model to optogenetically modified mice with remotely controlled regulation of selected neuronal populations by light may lead to very precise identification of neuronal circuits involved in coding addiction-related behaviors.

Paper Details

Date Published: 25 November 2014
PDF: 6 pages
Proc. SPIE 9290, Photonics Applications in Astronomy, Communications, Industry, and High-Energy Physics Experiments 2014, 92900U (25 November 2014); doi: 10.1117/12.2076054
Show Author Affiliations
Maria Nalberczak, Nencki Institute of Experimental Biology (Poland)
Kasia Radwanska, Nencki Institute of Experimental Biology (Poland)


Published in SPIE Proceedings Vol. 9290:
Photonics Applications in Astronomy, Communications, Industry, and High-Energy Physics Experiments 2014
Ryszard S. Romaniuk, Editor(s)

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