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Proceedings Paper

Optical biosensor system for the quick and reliable detection of virus infections: VIROSENS
Author(s): Günther Proll; Anja Hartjes; Alexander Sinclair; Goran Markovic; Florian Pröll; Pranav Patel; Matthias Niedrig
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Paper Abstract

Viral infections are of special threat because they can induce severe courses of disease but only few medical treatments are available. Because of socio-economic and climate changes, increased worldwide mobility and population growth, the risk of newly occurring and quickly spreading viral pathogens has increased. A diagnosis of these diseases at an early stage is essential for a quick risk assessment and a proper health management as well as patient’s treatment in an optimal way. Currently, the diagnosis of such diseases is based on time consuming and costly detection methods that can only be performed by specially trained personnel in laboratories at specific security levels. Aim of the project VIROSENS is the development of a biosensor platform that can specifically detect virus particles as well as virus-specific antibodies out of biological matrices like blood, serum, plasma and other body fluids. For this purpose, a disposable cartridge for such antibody- and virus-arrays is designed and developed within the project. The optical detection of viruses is performed with a portable device that will be benchmarked and evaluated concerning currently used standard detection methods in terms of its analytical performance. Within this project, a novel combination of serological tests and direct detection of virus particles will be developed, which will provide faster and more reliable results than presently available and used test systems.

Paper Details

Date Published: 31 October 2014
PDF: 6 pages
Proc. SPIE 9253, Optics and Photonics for Counterterrorism, Crime Fighting, and Defence X; and Optical Materials and Biomaterials in Security and Defence Systems Technology XI, 92530S (31 October 2014); doi: 10.1117/12.2073841
Show Author Affiliations
Günther Proll, Biametrics GmbH (Germany)
Anja Hartjes, Biametrics GmbH (Germany)
Alexander Sinclair, Biametrics GmbH (Germany)
Goran Markovic, Biametrics GmbH (Germany)
Florian Pröll, Biametrics GmbH (Germany)
Pranav Patel, Robert Koch-Institut (Germany)
Matthias Niedrig, Robert Koch-Institut (Germany)


Published in SPIE Proceedings Vol. 9253:
Optics and Photonics for Counterterrorism, Crime Fighting, and Defence X; and Optical Materials and Biomaterials in Security and Defence Systems Technology XI
Roberto Zamboni; Douglas Burgess; Gari Owen; François Kajzar; Attila A. Szep; Harbinder Rana, Editor(s)

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