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Proceedings Paper

Optical functional imaging of retina using stimulus-evoked intrinsic optical signals
Author(s): Yuhong Yang; Shuangyun Shao; Bei Tian; Xueqian Guo
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Paper Abstract

Without dying and fluorescently labeled markers on tissues, Intrinsic optical signals (IOSs) detection technology is a promising method to detect retinal function without influence on normal activities of organism. Slow IOSs of retina reflect the activities in inner retina and the middle layer of retina. In this paper, an IOSs’ detection system was built to detect slow IOSs based clinical instrument, Heidelberg Retina Angiograph 2(HAR2). The retina was illuminated by near infrared light continuously during the experiments. The visible light was presented to stimulate the retina. After image alignment and image processing, the signal-to-noise ratio of the IOSs was improved and the signal changes can be extracted. The experimental results showed that the present detection system is suitable to obtain the slow IOSs in clinic and IOSs detection technology is an effective noninvasive method to study changes of function of retina.

Paper Details

Date Published: 20 November 2014
PDF: 6 pages
Proc. SPIE 9268, Optics in Health Care and Biomedical Optics VI, 92682N (20 November 2014); doi: 10.1117/12.2073567
Show Author Affiliations
Yuhong Yang, Beijing Jiaotong Univ. (China)
Shuangyun Shao, Beijing Jiaotong Univ. (China)
Bei Tian, Capital Medical Univ. (China)
Xueqian Guo, Capital Medical Univ. (China)


Published in SPIE Proceedings Vol. 9268:
Optics in Health Care and Biomedical Optics VI
Qingming Luo; Xingde Li; Ying Gu; Yuguo Tang, Editor(s)

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