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Proceedings Paper

Detection of protein kinases P38 based on reflectance spectroscopy with n-type porous silicon microcavities for diagnosing hydatidosis hydatid disease
Author(s): Xiaoyi Lv; Guodong Lv; Zhenhong Jia; Jiajia Wang; Jiaqing Mo
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Paper Abstract

Detection of protein kinases P38 of Echinococcus granulosus and its homologous antibody have great value for early diagnosis and treatment of hydatidosis hydatid disease. In this experiment, n-type mesoporous silicon microcavities have been successfully fabricated without KOH etching or oxidants treatment that reported in other literature. We observed the changes of the reflectivity spectrum before and after the antigen-antibody reaction by n-type mesoporous silicon microcavities. The binding of protein kinases P38 and its homologous antibody causes red shifts in the reflection spectrum of the sensor, and the red shift was proportional to the protein kinases P38 concentration with linear relationship.

Paper Details

Date Published: 20 November 2014
PDF: 6 pages
Proc. SPIE 9268, Optics in Health Care and Biomedical Optics VI, 92681Q (20 November 2014); doi: 10.1117/12.2071332
Show Author Affiliations
Xiaoyi Lv, Xinjiang Univ. (China)
Guodong Lv, The First Teaching Hospital of Xinjiang Medical Univ. (China)
Zhenhong Jia, Xinjiang Univ. (China)
Jiajia Wang, Xinjiang Univ. (China)
Jiaqing Mo, Xinjiang Univ (China)


Published in SPIE Proceedings Vol. 9268:
Optics in Health Care and Biomedical Optics VI
Qingming Luo; Xingde Li; Ying Gu; Yuguo Tang, Editor(s)

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