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Proceedings Paper

Novel optimization method for multi-dimensional breast photoacoustic tomography
Author(s): Meng Cao; Ting Feng; Jie Yuan; Sidan Du; Xiaojun Liu; Xueding Wang; Paul L. Carson
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Paper Abstract

Photoacoustic tomography (PAT) is an effective optical biomedical imaging method which is characterized with noninonizing and noninvasive, presenting good soft tissue contrast with excellent spatial resolution. To build a multi-dimensional breast PAT image, more ultrasound sensors are needed, which brings difficulties to data acquisition. The time complexity for multi-dimensional breast PAT image reconstruction also rises tremendously. Compressive sensing (CS) theory breaks the restriction of Nyquist sampling theorem and is capable to rebuild signals with fewer measurements. In this contribution, we propose an effective optimization method for multi-dimensional breast PAT, which combines the theory of CS and an unevenly, adaptively distributing data acquisition algorithm. With this method, the quality of our reconstructed breast PAT images are better than those using existing multi-dimensional breast PAT system. To build breast PAT images with the same quality, the required number of ultrasound transducers is decreased by using our proposed method. We have verified our method on simulation data and achieved expected results in both two dimensional and three dimensional PAT image reconstruction. In the future, our method can be applied to various aspects of biomedical PAT imaging such as early stage tumor detection and in vivo imaging monitoring.

Paper Details

Date Published: 20 November 2014
PDF: 6 pages
Proc. SPIE 9268, Optics in Health Care and Biomedical Optics VI, 92681H (20 November 2014); doi: 10.1117/12.2070977
Show Author Affiliations
Meng Cao, Nanjing Univ. (China)
Ting Feng, Nanjing Univ. (China)
Jie Yuan, Nanjing Univ. (China)
Sidan Du, Nanjing Univ. (China)
Xiaojun Liu, Nanjing Univ. (China)
Xueding Wang, Univ. of Michigan (United States)
Paul L. Carson, Univ. of Michigan (United States)


Published in SPIE Proceedings Vol. 9268:
Optics in Health Care and Biomedical Optics VI
Qingming Luo; Xingde Li; Ying Gu; Yuguo Tang, Editor(s)

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