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Proceedings Paper

A novel method for speckle reduction in optical coherence tomography by image registration
Author(s): Hang Zhang; Zhongliang Li; Xiangzhao Wang; Nan Nan; Xuan Wang
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Paper Abstract

Speckle noise is a key factor that can influence the image quality of optical coherence tomography (OCT). The averaging of multiple B-scans can effectively suppress the speckle noise. Because of the sample motion, the images have to be exactly aligned before averaging. In this paper, we propose a new method for OCT image registration that combines global and local registration. The method is able to align the large global displacements in axial and lateral directions, as well as local displacements caused by non-linear deformation between images. Compared with other OCT image registration methods, our method improves the signal-to-noise ratio and contrast-to-noise ratio.

Paper Details

Date Published: 17 September 2014
PDF: 9 pages
Proc. SPIE 9230, Twelfth International Conference on Photonics and Imaging in Biology and Medicine (PIBM 2014), 92301Y (17 September 2014); doi: 10.1117/12.2068846
Show Author Affiliations
Hang Zhang, Shanghai Institute of Optics and Fine Mechanics (China)
Univ. of Chinese Academy of Sciences (China)
Zhongliang Li, Shanghai Institute of Optics and Fine Mechanics (China)
Univ. of Chinese Academy of Sciences (China)
Xiangzhao Wang, Shanghai Institute of Optics and Fine Mechanics (China)
Univ. of Chinese Academy of Sciences (China)
Nan Nan, Shanghai Institute of Optics and Fine Mechanics (China)
Univ. of Chinese Academy of Sciences (China)
Xuan Wang, Shanghai Institute of Optics and Fine Mechanics (China)
Univ. of Chinese Academy of Sciences (China)


Published in SPIE Proceedings Vol. 9230:
Twelfth International Conference on Photonics and Imaging in Biology and Medicine (PIBM 2014)
Qingming Luo; Lihong V. Wang; Valery V. Tuchin, Editor(s)

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