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Proceedings Paper

Miniature spectrometer and multispectral imager as a potential diagnostic aid in dermatology
Author(s): Haishan Zeng; Calum E. MacAulay; David I. McLean; Harvey Lui; Branko Palcic
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Paper Abstract

A miniature spectrometer system has been constructed for both reflectance and autofluorescence spectral measurements of skin. The system is based on PC plug-in spectrometer, therefore, it is miniature and easy to operate. The spectrometer has been used clinically to collect spectral data from various skin lesions including skin cancer. To date, 48 patients with a total of 71 diseased skin sites have been measured. Analysis of these preliminary data suggests that unique spectral characteristics exist for certain types of skin lesions, i.e. seborrheic keratosis, psoriasis, etc.. These spectral characteristics will help the differential diagnosis in Dermatology practice. In conjunction with the spectral point measurements, we are building and testing a multispectral imaging system to measure the spatial distribution of skin reflectance and autofluorescence. Preliminary results indicate that a cutaneous squamous cell carcinoma has a weak autofluorescence signal at the edge of the lesion, but a higher autofluorescence signal in the central area.

Paper Details

Date Published: 12 April 1995
PDF: 5 pages
Proc. SPIE 2387, Advances in Laser and Light Spectroscopy to Diagnose Cancer and Other Diseases II, (12 April 1995); doi: 10.1117/12.206836
Show Author Affiliations
Haishan Zeng, British Columbia Cancer Agency (Canada)
Calum E. MacAulay, British Columbia Cancer Agency (Canada)
David I. McLean, British Columbia Cancer Agency (Canada)
Harvey Lui, British Columbia Cancer Agency (Canada)
Branko Palcic, British Columbia Cancer Agency (Canada)

Published in SPIE Proceedings Vol. 2387:
Advances in Laser and Light Spectroscopy to Diagnose Cancer and Other Diseases II
Robert R. Alfano, Editor(s)

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