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Proceedings Paper

Direct electronic probing of biological complexes formation
Author(s): Eleonora Macchia; Maria Magliulo; Kyriaki Manoli; Francesco Giordano; Gerardo Palazzo; Luisa Torsi
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Paper Abstract

Functional bio-interlayer organic field - effect transistors (FBI-OFET), embedding streptavidin, avidin and neutravidin as bio-recognition element, have been studied to probe the electronic properties of protein complexes. The threshold voltage control has been achieved modifying the SiO2 gate diaelectric surface by means of the deposition of an interlayer of bio-recognition elements. A threshold voltage shift with respect to the unmodified dielectric surface toward more negative potential values has been found for the three different proteins, in agreement with their isoelectric points. The relative responses in terms of source – drain current, mobility and threshold voltage upon exposure to biotin of the FBI-OFET devices have been compared for the three bio-recognition elements.

Paper Details

Date Published: 3 October 2014
PDF: 10 pages
Proc. SPIE 9183, Organic Light Emitting Materials and Devices XVIII, 918302 (3 October 2014); doi: 10.1117/12.2067934
Show Author Affiliations
Eleonora Macchia, Univ. degli Studi di Bari Aldo Moro (Italy)
Maria Magliulo, Univ. degli Studi di Bari Aldo Moro (Italy)
Kyriaki Manoli, Univ. degli Studi di Bari Aldo Moro (Italy)
Francesco Giordano, Univ. degli Studi di Bari Aldo Moro (Italy)
Gerardo Palazzo, Univ. degli Studi di Bari Aldo Moro (Italy)
Luisa Torsi, Univ. degli Studi di Bari Aldo Moro (Italy)


Published in SPIE Proceedings Vol. 9183:
Organic Light Emitting Materials and Devices XVIII
Franky So; Chihaya Adachi, Editor(s)

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